Paradosso di Levinthal: differenze tra le versioni

Il '''paradosso di Levinthal''' può essere considerato un enigma relativo alle dinamiche del [[folding]] proteico.

<!--In [[1969]] [[Cyrus Levinthal]] noted that, because of the very large number of [[degrees of freedom]] in an unfolded [[polypeptide chain]], the molecule has an astronomical number of possible conformations. (The estimate 10³⁰⁰ appears in the original article). If the protein is to attain its corrected folded configuration by sequentially sampling all the possible conformations, it would require a time longer than the age of universe to arrive at its correct native conformation. This is true even if conformations are sampled at rapid ([[nanosecond]] or [[picosecond]]) rates.