Differenze tra le versioni di "(N-acetilneuraminil)-galattosilglucosilceramide N-acetilgalattosaminiltransferasi"

nessun oggetto della modifica
| didascalia =
| ECnumber = 2.4.1.92
| nome sistematico = UDP-''N''-acetylacetil-<small>D</small>-galactosaminegalattosammina:1-''O''-[''O''-(''N''-acetylacetil-&alpha;α-neuraminosylneuraminosil)-(2&rarr;3)-''O''-&beta;β-<small>D</small>-galactopyranosylgalattopiranosil-(1&rarr;4)-&beta;β-<small>D</small>-glucopyranosylglucopiranosil]-ceramide 1,4-&beta;β-''N''-acetylacetil-<small>D</small>-galactosaminyltransferasegalattosamminiltransferasi
| altri nomi = uridineuridina diphosphoacetylgalactosaminedifosfoacetilgalattosammina-ganglioside GM3 acetylgalactosaminyltransferaseacetilgalattosamminiltransferasi; ganglioside GM2 synthasesintasi; ganglioside GM3 acetylgalactosaminyltransferaseacetilgalattosamminiltransferasi; GM2 synthasesintasi; UDP acetylgalactosamineacetilgalattosammina-(''N''-acetylneuraminylacetilneuraminil)-<small>D</small>-galactosylgalattosil-<small>D</small>-glucosylceramideglucosilceramide acetylgalactosaminyltransferaseacetilgalattosamminiltransferasi; UDP-''N''-acetylgalactosamineacetilgalattosammina GM3 ''N''-acetylgalactosaminyltransferaseacetilgalattosamminiltransferasi; uridineuridina diphosphoacetylgalactosaminedifosfoacetilgalattosammina-acetylneuraminylgalactosylglucosylceramideacetilneuraminilgalattosilglucosilceramide acetylgalactosaminyltransferaseacetilgalattosamminiltransferasi; uridineuridina diphosphoacetylgalactosaminedifosfoacetilgalattosammina-hematosideematoside acetylgalactosaminyltransferaseacetilgalattosamminiltransferasi; GM2/GD2-synthasesintasi; &beta;β-1,4''N''-aetylgalactosaminyltransferaseacetilgalattosamminiltransferasi; asialo-GM2 synthasesintasi; GalNAc-T; UDP-''N''-acetylacetil-<small>D</small>-galactosaminegalattosammina:(''N''-acetylneuraminylacetilneuraminil)-<small>D</small>-galactosylgalattosil-<small>D</small>-glucosylceramideglucosilceramide ''N''-acetylacetil-<small>D</small>-galactosaminyltransferasegalattosamminiltransferasi
}}
 
La '''(N-acetilneuraminil)-galattosilglucosilceramide N-acetilgalattosaminiltransferasi''' è un [[enzima]] appartenente alla classe delle [[transferasi]], che catalizza la seguente [[reazione chimica|reazione]]:
:UDP-''N''-acetylacetil-<small>D</small>-galactosamine[[galattosammina]] + 1-''O''-[''O''-(''N''-acetylacetil-&alpha;α-neuraminosylneuraminosil)-(2&rarr;3)-''O''-&beta;β-<small>D</small>-galactopyranosylgalattopiranosil-(1&rarr;4)-&beta;β-<small>D</small>-glucopyranosylglucopiranosil]-[[ceramide]] {{Unicode|⇄}} [[UDP]] + 1-''O''-[''O''-2-(acetylaminoacetilammino)-2-deoxydeossi-&beta;β-<small>D</small>-galactopyranosylgalattopiranosil-(1&rarr;4)-''O''-[''N''-acetylacetil-&alpha;α-neuraminosylneuraminosil-(2&rarr;3)]-''O''-&beta;β-<small>D</small>-galactopyranosylgalattopiranosil-(1&rarr;4)-&beta;β-<small>D</small>-glucopyranosylglucopiranosil]-ceramide
ThisQuesto enzymeenzima catalysescatalizza thela formationformazione ofdei the gangliosides[[gangliosidi]] (i.e. sialic-acid-containing[[glicosfingolipidi]] glycosphingolipidscontenenti [[acido sialico]]) GM2, GD2 ande SM2 fromdal GM3, GD3 ande SM3, respectivelyrispettivamente. AsialoL'asialo-GM3 [3] ande la lactosylceramidelattosilceramide [2] aresono alsoanche substrates[[substrati]], butmentre glycoproteinsle and[[glicoproteine]] oligosaccharidese gli [[oligosaccaridi]] arenon notsono substratessustrati.
 
== Bibliografia ==
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