Berberina: differenze tra le versioni

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→‎Farmacodinamica: ref. e testo
Riga 47:
Ha anche proprietà soppressive sulla produzione di citochine proinfiammatorie.<ref name="pmid19874221">{{cite journal | author = Hu Y, Chen X, Duan H, Hu Y, Mu X | title = Chinese herbal medicinal ingredients inhibit secretion of IL-6, IL-8, E-selectin and TXB2 in LPS-induced rat intestinal microvascular endothelial cells | journal = Immunopharmacol Immunotoxicol | volume = 31 | issue = 4 | pages = 550–5 | year = 2009 | id = PMID 19874221 | doi = 10.3109/08923970902814129 | url = | issn = }}</ref>
 
Recentemente viene studiato per le sue documentate proprietà:
Recentemente viene studiato per le sue documentate proprietà anticancro<ref>{{cite journal | author = Sun Y, Xun K, Wang Y, Chen X | title = A systematic review of the anticancer properties of berberine, a natural product from Chinese herbs | journal = Anticancer Drugs | volume = 20 | issue = 9 | pages = 757–69 | date = October 2009 | id = PMID 19704371 | doi = 10.1097/CAD.0b013e328330d95b }}</ref><ref>{{cite journal | vauthors = Tang J, Feng Y, Tsao S, Wang N, Curtain R, Wang Y | title = Berberine and Coptidis Rhizoma as novel antineoplastic agents: a review of traditional use and biomedical investigations | journal = Journal of Ethnopharmacology | volume = 126 | issue = 1 | pages = 5–17 | date = August 2009 | id = PMID 19686830 | doi = 10.1016/j.jep.2009.08.009 }}</ref> <ref>{{cite journal | author = Serafim TL, Oliveira PJ, Sardao VA, Perkins E, Parke D, Holy J | title = Different concentrations of berberine result in distinct cellular localization patterns and cell cycle effects in a melanoma cell line | journal = Cancer Chemotherapy and Pharmacology | volume = 61 | issue = 6 | pages = 1007–18 | date = May 2008 | id = PMID 17661039 | doi = 10.1007/s00280-007-0558-9 }}</ref><ref>{{cite journal | author = Pinto-Garcia L, Efferth T, Torres A, Hoheisel JD, Youns M | title = Berberine Inhibits Cell Growth and Mediates Caspase-Independent Cell Death in Human Pancreatic Cancer Cells | journal = Planta Medica | volume = 76 | issue = 11 | pages = 1155–61 | date = May 2010 | id = PMID 20455200 | doi = 10.1055/s-0030-1249931 }}</ref><ref>{{cite journal | author = Ho YT, Lu CC, Yang JS, Chiang JH, Li TC, Ip SW, Hsia TC, Liao CL, Lin JG, Wood WG, Chung JG | title = Berberine induced apoptosis via promoting the expression of caspase-8, -9 and -3, apoptosis-inducing factor and endonuclease G in SCC-4 human tongue squamous carcinoma cancer cells | journal = Anticancer Research | volume = 29 | issue = 10 | pages = 4063–70 | date = October 2009 | id = PMID 19846952 | url = http://ar.iiarjournals.org/cgi/pmidlookup?view=long&pmid=19846952 }}</ref> e cardiologiche,<ref>{{cite journal | author = Qi MY, Feng Y, Dai DZ, Li N, Cheng YS, Dai Y | title = CPU86017, a berberine derivative, attenuates cardiac failure through normalizing calcium leakage and downregulated phospholamban and exerting antioxidant activity | journal = Acta Pharmacol Sin | volume = 31 | issue = 2 | pages = 165–74 | date = February 2010 |id = PMID 20139899 | pmc = 4002834 | doi = 10.1038/aps.2009.180 | url = http://www.nature.com/aps/journal/v31/n2/abs/aps2009180a.html }}</ref><ref>{{cite journal | author = Huang WM, Yan H, Jin JM, Yu C, Zhang H | title = Beneficial effects of berberine on hemodynamics during acute ischemic left ventricular failure in dogs | journal = Chinese Medical Journal | volume = 105 | issue = 12 | pages = 1014–9 | date = December 1992 | id = PMID 1299549 }}</ref><ref>{{cite journal | author = Riccioppo Neto F | title = Electropharmacological effects of berberine on canine cardiac Purkinje fibres and ventricular muscle and atrial muscle of the rabbit | journal = British Journal of Pharmacology | volume = 108 | issue = 2 | pages = 534–7 | date = February 1993 | id = PMID 8448600 | pmc = 1908004 | doi = 10.1111/j.1476-5381.1993.tb12836.x }}</ref><ref>{{cite journal | author = Marin-Neto JA, Maciel BC, Secches AL, Gallo Júnior L | title = Cardiovascular effects of berberine in patients with severe congestive heart failure | journal = Clinical Cardiology | volume = 11 | issue = 4 | pages = 253–60 | date = April 1988 | id = PMID 3365876 | doi = 10.1002/clc.4960110411 }}</ref><ref>{{cite journal | author = Zeng XH, Zeng XJ, Li YY | title = Efficacy and safety of berberine for congestive heart failure secondary to ischemic or idiopathic dilated cardiomyopathy | journal = The American Journal of Cardiology | volume = 92 | issue = 2 | pages = 173–6 | date = July 2003 | id = PMID 12860219 | doi = 10.1016/S0002-9149(03)00533-2 }}</ref><ref>Wu M., Wang J., Liu L.-T. "Advance of studies on anti-atherosclerosis mechanism of berberine", Chinese Journal of Integrative Medicine 2010 16:2 (188-192)</ref><ref>{{cite journal | author = Kim JB, Yu JH, Ko E, Lee KW, Song AK, Park SY, Shin I, Han W, Noh DY | title = The alkaloid Berberine inhibits the growth of Anoikis-resistant MCF-7 and MDA-MB-231 breast cancer cell lines by inducing cell cycle arrest | journal = Phytomedicine | volume = 17 | issue = 6 | pages = 436–40 | date = October 2009 | id = PMID 19800775 | doi = 10.1016/j.phymed.2009.08.012 }}</ref> oltre che metaboliche.
* anticancro<ref>{{cite journal | author = Sun Y, Xun K, Wang Y, Chen X | title = A systematic review of the anticancer properties of berberine, a natural product from Chinese herbs | journal = Anticancer Drugs | volume = 20 | issue = 9 | pages = 757–69 | date = October 2009 | id = PMID 19704371 | doi = 10.1097/CAD.0b013e328330d95b }}</ref><ref>{{cite journal | vauthors = Tang J, Feng Y, Tsao S, Wang N, Curtain R, Wang Y | title = Berberine and Coptidis Rhizoma as novel antineoplastic agents: a review of traditional use and biomedical investigations | journal = Journal of Ethnopharmacology | volume = 126 | issue = 1 | pages = 5–17 | date = August 2009 | id = PMID 19686830 | doi = 10.1016/j.jep.2009.08.009 }}</ref> <ref>{{cite journal | author = Serafim TL, Oliveira PJ, Sardao VA, Perkins E, Parke D, Holy J | title = Different concentrations of berberine result in distinct cellular localization patterns and cell cycle effects in a melanoma cell line | journal = Cancer Chemotherapy and Pharmacology | volume = 61 | issue = 6 | pages = 1007–18 | date = May 2008 | id = PMID 17661039 | doi = 10.1007/s00280-007-0558-9 }}</ref><ref>{{cite journal | author = Pinto-Garcia L, Efferth T, Torres A, Hoheisel JD, Youns M | title = Berberine Inhibits Cell Growth and Mediates Caspase-Independent Cell Death in Human Pancreatic Cancer Cells | journal = Planta Medica | volume = 76 | issue = 11 | pages = 1155–61 | date = May 2010 | id = PMID 20455200 | doi = 10.1055/s-0030-1249931 }}</ref><ref>{{cite journal | author = Ho YT, Lu CC, Yang JS, Chiang JH, Li TC, Ip SW, Hsia TC, Liao CL, Lin JG, Wood WG, Chung JG | title = Berberine induced apoptosis via promoting the expression of caspase-8, -9 and -3, apoptosis-inducing factor and endonuclease G in SCC-4 human tongue squamous carcinoma cancer cells | journal = Anticancer Research | volume = 29 | issue = 10 | pages = 4063–70 | date = October 2009 | id = PMID 19846952 | url = http://ar.iiarjournals.org/cgi/pmidlookup?view=long&pmid=19846952 }}</ref><ref>{{cite journal | author = Ho YT, Lu CC, Yang JS, Chiang JH, Li TC, Ip SW, Hsia TC, Liao CL, Lin JG, Wood WG, Chung JG | title = Berberine induced apoptosis via promoting the expression of caspase-8, -9 and -3, apoptosis-inducing factor and endonuclease G in SCC-4 human tongue squamous carcinoma cancer cells | journal = Anticancer Research | volume = 29 | issue = 10 | pages = 4063–70 | date = October 2009 | id = PMID 19846952 | url = http://ar.iiarjournals.org/cgi/pmidlookup?view=long&pmid=19846952 }}</ref><ref>{{cite journal | vauthors = Auyeung KK, Ko JK | title = Coptis chinensis inhibits hepatocellular carcinoma cell growth through nonsteroidal anti-inflammatory drug-activated gene activation | journal = International journal of molecular medicine | volume = 24 | issue = 4 | pages = 571–7 | date = October 2009 | pmid = 19724899 | doi = 10.3892/ijmm_00000267 }}</ref><ref>{{cite journal | author = Tang F, Wang D, Duan C, Huang D, Wu Y, Chen Y, Wang W, Xie C, Meng J, Wang L, Wu B, Liu S, Tian D, Zhu F, He Z, Deng F, Cao Y | title = Berberine inhibits metastasis of nasopharyngeal carcinoma 5-8F cells by targeting Rho kinase-mediated Ezrin phosphorylation at threonine 567 | journal = The Journal of Biological Chemistry | volume = 284 | issue = 40 | pages = 27456–66 | date = October 2009 | id = PMID 19651779 | pmc = 2785675 | doi = 10.1074/jbc.M109.033795 }}</ref>
 
Recentemente viene studiato per le sue documentate proprietà anticancro<ref>{{cite journal | author = Sun Y, Xun K, Wang Y, Chen X | title = A systematic review of the anticancer properties of berberine, a natural product from Chinese herbs | journal = Anticancer Drugs | volume = 20 | issue = 9 | pages = 757–69 | date = October 2009 | id = PMID 19704371 | doi = 10.1097/CAD.0b013e328330d95b }}</ref><ref>{{cite journal | vauthors = Tang J, Feng Y, Tsao S, Wang N, Curtain R, Wang Y | title = Berberine and Coptidis Rhizoma as novel antineoplastic agents: a review of traditional use and biomedical investigations | journal = Journal of Ethnopharmacology | volume = 126 | issue = 1 | pages = 5–17 | date = August 2009 | id = PMID 19686830 | doi = 10.1016/j.jep.2009.08.009 }}</ref> <ref>{{cite journal | author = Serafim TL, Oliveira PJ, Sardao VA, Perkins E, Parke D, Holy J | title = Different concentrations of berberine result in distinct cellular localization patterns and cell cycle effects in a melanoma cell line | journal = Cancer Chemotherapy and Pharmacology | volume = 61 | issue = 6 | pages = 1007–18 | date = May 2008 | id = PMID 17661039 | doi = 10.1007/s00280-007-0558-9 }}</ref><ref>{{cite journal | author = Pinto-Garcia L, Efferth T, Torres A, Hoheisel JD, Youns M | title = Berberine Inhibits Cell Growth and Mediates Caspase-Independent Cell Death in Human Pancreatic Cancer Cells | journal = Planta Medica | volume = 76 | issue = 11 | pages = 1155–61 | date = May 2010 | id = PMID 20455200 | doi = 10.1055/s-0030-1249931 }}</ref><ref>{{cite journal | author = Ho YT, Lu CC, Yang JS, Chiang JH, Li TC, Ip SW, Hsia TC, Liao CL, Lin JG, Wood WG, Chung JG | title = Berberine induced apoptosis via promoting the expression of caspase-8, -9 and -3, apoptosis-inducing factor and endonuclease G in SCC-4 human tongue squamous carcinoma cancer cells | journal = Anticancer Research | volume = 29 | issue = 10 | pages = 4063–70 | date = October 2009 | id = PMID 19846952 | url = http://ar.iiarjournals.org/cgi/pmidlookup?view=long&pmid=19846952 }}</ref> e *cardiologiche,<ref>{{cite journal | author = Qi MY, Feng Y, Dai DZ, Li N, Cheng YS, Dai Y | title = CPU86017, a berberine derivative, attenuates cardiac failure through normalizing calcium leakage and downregulated phospholamban and exerting antioxidant activity | journal = Acta Pharmacol Sin | volume = 31 | issue = 2 | pages = 165–74 | date = February 2010 |id = PMID 20139899 | pmc = 4002834 | doi = 10.1038/aps.2009.180 | url = http://www.nature.com/aps/journal/v31/n2/abs/aps2009180a.html }}</ref><ref>{{cite journal | author = Huang WM, Yan H, Jin JM, Yu C, Zhang H | title = Beneficial effects of berberine on hemodynamics during acute ischemic left ventricular failure in dogs | journal = Chinese Medical Journal | volume = 105 | issue = 12 | pages = 1014–9 | date = December 1992 | id = PMID 1299549 }}</ref><ref>{{cite journal | author = Riccioppo Neto F | title = Electropharmacological effects of berberine on canine cardiac Purkinje fibres and ventricular muscle and atrial muscle of the rabbit | journal = British Journal of Pharmacology | volume = 108 | issue = 2 | pages = 534–7 | date = February 1993 | id = PMID 8448600 | pmc = 1908004 | doi = 10.1111/j.1476-5381.1993.tb12836.x }}</ref><ref>{{cite journal | author = Marin-Neto JA, Maciel BC, Secches AL, Gallo Júnior L | title = Cardiovascular effects of berberine in patients with severe congestive heart failure | journal = Clinical Cardiology | volume = 11 | issue = 4 | pages = 253–60 | date = April 1988 | id = PMID 3365876 | doi = 10.1002/clc.4960110411 }}</ref><ref>{{cite journal | author = Zeng XH, Zeng XJ, Li YY | title = Efficacy and safety of berberine for congestive heart failure secondary to ischemic or idiopathic dilated cardiomyopathy | journal = The American Journal of Cardiology | volume = 92 | issue = 2 | pages = 173–6 | date = July 2003 | id = PMID 12860219 | doi = 10.1016/S0002-9149(03)00533-2 }}</ref><ref>Wu M., Wang J., Liu L.-T. "Advance of studies on anti-atherosclerosis mechanism of berberine", Chinese Journal of Integrative Medicine 2010 16:2 (188-192)</ref><ref>{{cite journal | author = Kim JB, Yu JH, Ko E, Lee KW, Song AK, Park SY, Shin I, Han W, Noh DY | title = The alkaloid Berberine inhibits the growth of Anoikis-resistant MCF-7 and MDA-MB-231 breast cancer cell lines by inducing cell cycle arrest | journal = Phytomedicine | volume = 17 | issue = 6 | pages = 436–40 | date = October 2009 | id = PMID 19800775 | doi = 10.1016/j.phymed.2009.08.012 }}</ref> oltre che metaboliche.
*metaboliche.
 
== Note ==