Berberina: differenze tra le versioni

Contenuto cancellato Contenuto aggiunto
Riga 44:
La berberina è [[ligando]] [[agonista]] del [[Recettore sigma-1]] e 2 ed è anche un agonista del [[PPARγ]] (Peroxisome proliferator-activated receptor gamma).
 
Possiede inoltre attività antibatterica<ref name="pmid16379555">{{cite journal | author = Yu HH, Kim KJ, Cha JD, Kim HK, Lee YE, Choi NY, You YO | title = Antimicrobial activity of berberine alone and in combination with ampicillin or oxacillin against methicillin-resistant Staphylococcus aureus | journal = J Med Food | volume = 8 | issue = 4 | pages = 454–61 | year = 2005 | id = PMID 16379555 | doi = 10.1089/jmf.2005.8.454 | url = | issn = }}</ref><ref>{{cite journal |doi=10.1111/j.1742-4658.2010.07680.x |title=Poster Presentations |year=2010 |journal=FEBS Journal |volume=277 |pages=37}}</ref><ref>Li Y., Zuo G.-Y. 'Advances in studies on antimicrobial activities of alkaloids" Chinese Traditional and Herbal Drugs 2010 41:6 (1006-1014)</ref><ref>{{cite journal | author = Stermitz FR, Lorenz P, Tawara JN, Zenewicz LA, Lewis K | title = Synergy in a medicinal plant: antimicrobial action of berberine potentiated by 5'-methoxyhydnocarpin, a multidrug pump inhibitor | journal = Proceedings of the National Academy of Sciences of the United States of America | volume = 97 | issue = 4 | pages = 1433–7 | date = February 2000 | id = PMID10677479PMID 10677479 | pmc = 26451 | doi = 10.1073/pnas.030540597 | bibcode = 2000PNAS...97.1433S }}</ref><ref>{{cite journal | author = Zhang S, Zhang B, Xing K, Zhang X, Tian X, Dai W | title = Inhibitory effects of golden thread (Coptis chinensis) and berberine on Microcystis aeruginosa | journal = Water Science & Technology | volume = 61 | issue = 3 | pages = 763 | year = 2010 | id = PMID 20150713 | doi = 10.2166/wst.2010.857 }}</ref> ed ha anche proprietà inibenti la produzione di [[citochina|citochine proinfiammatorie]].<ref name="pmid19874221">{{cite journal | author = Hu Y, Chen X, Duan H, Hu Y, Mu X | title = Chinese herbal medicinal ingredients inhibit secretion of IL-6, IL-8, E-selectin and TXB2 in LPS-induced rat intestinal microvascular endothelial cells | journal = Immunopharmacol Immunotoxicol | volume = 31 | issue = 4 | pages = 550–5 | year = 2009 | id = PMID 19874221 | doi = 10.3109/08923970902814129 | url = | issn = }}</ref>
Ha anche proprietà soppressive sulla produzione di citochine proinfiammatorie.<ref name="pmid19874221">{{cite journal | author = Hu Y, Chen X, Duan H, Hu Y, Mu X | title = Chinese herbal medicinal ingredients inhibit secretion of IL-6, IL-8, E-selectin and TXB2 in LPS-induced rat intestinal microvascular endothelial cells | journal = Immunopharmacol Immunotoxicol | volume = 31 | issue = 4 | pages = 550–5 | year = 2009 | id = PMID 19874221 | doi = 10.3109/08923970902814129 | url = | issn = }}</ref>
 
== Clinica ==