Berberina: differenze tra le versioni

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Riga 44:
La berberina è [[ligando]] [[agonista]] del [[recettore sigma-1]] e 2 ed è anche un agonista del [[PPARγ]] (Peroxisome proliferator-activated receptor gamma).
 
Possiede attività antimicrobiche su batteri, virus, funghi, protozoi, elminti, e [[clamidia]].<ref name="pmid10767672">{{cite journal | author = | title = Berberine | journal = Altern Med Rev | volume = 5 | issue = 2 | pages = 175–7 | year = 2000 | id = PMID 10767672 | doi = | url = | issn = }}</ref><ref name="pmid16379555">{{cite journal | author = Yu HH, Kim KJ, Cha JD, Kim HK, Lee YE, Choi NY, You YO | title = Antimicrobial activity of berberine alone and in combination with ampicillin or oxacillin against methicillin-resistant Staphylococcus aureus | journal = J Med Food | volume = 8 | issue = 4 | pages = 454–61 | year = 2005 | id = PMID 16379555 | doi = 10.1089/jmf.2005.8.454 | url = | issn = }}</ref><ref>{{cite journal |doi=10.1111/j.1742-4658.2010.07680.x |title=Poster Presentations |year=2010 |journal=FEBS Journal |volume=277 |pages=37}}</ref><ref>Li Y., Zuo G.-Y. 'Advances in studies on antimicrobial activities of alkaloids" Chinese Traditional and Herbal Drugs 2010 41:6 (1006-1014)</ref><ref>{{cite journal | author = Stermitz FR, Lorenz P, Tawara JN, Zenewicz LA, Lewis K | title = Synergy in a medicinal plant: antimicrobial action of berberine potentiated by 5'-methoxyhydnocarpin, a multidrug pump inhibitor | journal = Proceedings of the National Academy of Sciences of the United States of America | volume = 97 | issue = 4 | pages = 1433–7 | date = February 2000 | id = PMID 10677479 | pmc = 26451 | doi = 10.1073/pnas.030540597 | bibcode = 2000PNAS...97.1433S }}</ref><ref>{{cite journal | author = Zhang S, Zhang B, Xing K, Zhang X, Tian X, Dai W | title = Inhibitory effects of golden thread (Coptis chinensis) and berberine on Microcystis aeruginosa | journal = Water Science & Technology | volume = 61 | issue = 3 | pages = 763 | year = 2010 | id = PMID 20150713 | doi = 10.2166/wst.2010.857 }}</ref><ref name="pmid26760994">{{cite journal | author = Manosalva L, Mutis A, Urzúa A, Fajardo V, Quiroz A | title = Antibacterial Activity of Alkaloid Fractions from Berberis microphylla G. Forst and Study of Synergism with Ampicillin and Cephalothin | journal = Molecules | volume = 21 | issue = 1 | pages = | year = 2016 | id = PMID 26760994 | doi = 10.3390/molecules21010076 | url = | issn = }}</ref> inoltre, ha anche proprietà inibenti la produzione di [[citochina|citochine proinfiammatorie]].<ref name="pmid19874221">{{cite journal | author = Hu Y, Chen X, Duan H, Hu Y, Mu X | title = Chinese herbal medicinal ingredients inhibit secretion of IL-6, IL-8, E-selectin and TXB2 in LPS-induced rat intestinal microvascular endothelial cells | journal = Immunopharmacol Immunotoxicol | volume = 31 | issue = 4 | pages = 550–5 | year = 2009 | id = PMID 19874221 | doi = 10.3109/08923970902814129 | url = | issn = }}</ref><ref name="pmid26102009">{{cite journal | author = Niu X, Zhang H, Li W, Wang Y, Mu Q, Wang X, He Z, Yao H | title = Protective effect of cavidine on acetic acid-induced murine colitis via regulating antioxidant, cytokine profile and NF-κB signal transduction pathways | journal = Chem. Biol. Interact. | volume = 239 | issue = | pages = 34–45 | year = 2015 | id = PMID 26102009 | doi = 10.1016/j.cbi.2015.06.026 | url = | issn = }}</ref><ref name="pmid26722438">{{cite journal | author = Ai F, Chen M, Yu B, Yang Y, Xu G, Gui F, Liu Z, Bai X, Chen Z | title = Berberine regulates proliferation, collagen synthesis and cytokine secretion of cardiac fibroblasts via AMPK-mTOR-p70S6K signaling pathway | journal = Int J Clin Exp Pathol | volume = 8 | issue = 10 | pages = 12509–16 | year = 2015 | id = PMID 26722438 | pmc = 4680383 | doi = | url = | issn = }}</ref>
 
== Clinica ==